Anti-parasite

Showing all 4 results

Product info

Catalog Id
Size
Price
a-210-100
100mg
69.00
a-210-10
10 g
84.00
Description

Albendazole is a benzimidazole derivative typically used as a comprehensive antiparasitic belonging to the anthelminthic group and works by disrupting microtubule formation. Microtubule disruption diminishes glucose transport which increases glycogen catabolism. Eventually, this net loss of energy results in tissue death.

The resulting tissue death caused by microtubule formation is a sought after mechanism in oncology research. In vitro research of albendazole on HNSCC (head and neck squamous cancer cells) had shown cell cycle arrest in G2/M stage, resulting in apoptosis. Disruption of microtubule formation also prevented malignant cell migration.

Product Specifications
Albendazole
Methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl) carbamate

Formula: C12H15N3O2S

MW: 265.33 g/mol

Storage/Handling: Store at room temperature.

PubChem Chemical ID: 2082

Product info

Catalog Id
Size
Price
d-910-5
5 x 1g
Description

Dimethylcarbamazine citrate salt (DEC) is an antiparasitic piperazine derivative that has been used against Wuchereria bancrofti. It is a stable compound in salt form and has been used to research antimalarial resistances in W. bancrofti. DEC inhibits arachidonic acid synthesis, which is a key component for a protective sheath formed by pre-larval W. bancrofti called microfilaria.

Product Specifications
Dimethylcarbamazine citrate salt
DEC-C

Formula: C10H21N3O ∙ C6H8O7

MW: 391.42 g/mol

Storage/Handling: Store desiccated at room temperature.

PubChem Chemical ID: 15432

Hazardous fees may apply for Air Shipments.

Product info

Catalog Id
Size
Price
i-700-1
1 g
Description

Ivermectin is a broad-spectrum antiparasitic drug of the avermectin family. Derived from Streptomyces avermitilis, ivermectin is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors. It also regulates glutamate-GABA-activated chloride channels.

The mechanism of ivermectin is not well understood. It is thought to target nematode neurotransmitters causing paralysis and death. Ivermectin also inhibits secretions of parasitic proteins necessary for parasites to evade the host immune system.

Ivermectin is insoluble.

Product Specifications
Ivermectin, USP Grade

Formula: C48H74O14

MW: 875.09 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 71308642

Air shipments may require special packaging and a small additional box charge.

Product info

Catalog Id
Size
Price
p-760-25
25 g
Description

Praziquantel is an anthelmintic drug used against schistosomes and cestodes. It functions by increasing the tegmentum permeability to calcium ions. This induces paralytic muscle contraction and death. Praziquantel is more effective on adult parasites than young parasites. It suppresses glucose uptake and stimulates lactate release.

Praziquantel is used to study voltage-gated calcium channels.

Product Specifications
Praziquantel

MOLECULAR BIOLOGY GRADE

Formula: C19H24N2O2

MW: 312.41 g/mol

Storage/Handling: Store at – 20 °C.  Soluble in alcohol and methylene chloride.

PubChem Chemical ID: 4891