Antibiotics

Showing 1–16 of 145 results

Product info

Catalog Id
Size
Price
a-530-1
1 g
90.00
a-530-5
5 g
244.00
Description

Amikacin hydrate is a broad-spectrum aminoglycoside antibiotic derived from kanamycin A. It is effective against gram-negative bacteria such as Pseudomonas aeruginosa and a variety of enteric species. It is also effective against Mycobacterium tuberculosis. Amikacin hydrate is freely soluble in aqueous solution.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Samples of microbes grown in the presence of a 30 μg amikacin disc with a zone of inhibition of <14 mm in diameter are considered resistant. Intermediate resistance zones of inhibition are typically 15 mm-16 mm in diameter.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Amikacin Hydrate

MOLECULAR BIOLOGY GRADE

Formula: C22H43N5O13 ∙ XH2O

MW: 585.60 g/mol (anhydrous)

Storage/Handling: Store desiccated at 2-8°C.

PubChem Chemical ID: 37768

Product info

Catalog Id
Size
Price
a-532-5
5 g
68.00
a-532-25
25 g
178.00
Description

Amikacin sulfate (disulfate) is a broad-spectrum aminoglycoside antibiotic derived from kanamycin A. It is effective against gram-negative bacteria such as Pseudomonas aeruginosa and a variety of enteric species. It is also effective against Mycobacterium tuberculosis. Amikacin sulfate is freely soluble in aqueous solution.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Amikacin Sulfate
Amikacin Disulfate

USP Grade

Formula: C22H43N5O13 ∙ 2H2SO4

MW: 781.76 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 19082597

Product info

Catalog Id
Size
Price
a-551-1
1 g
76.00
a-551-5
5 g
117.00
a-551-25
25 g
350.00
Description

Amoxicillin is an extended-spectrum ß-lactam antibiotic with a structure similar to that of ampicillin. It is effective against a variety of ß-lactamase negative bacteria including E. coli and various Streptococcus and Staphylococcus bacteria. It is also effective against a variety of other gram-negative and gram-positive bacteria. Amoxicillin sodium salt is freely soluble in aqueous solution.

Penicillins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a five-membered thiazolidine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Amoxicillin Sodium Salt

MOLECULAR BIOLOGY GRADE

Formula: C16H18N3NaO5S

MW: 387.39 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 23663126

Product info

Catalog Id
Size
Price
a-550-5
5 g
70.00
a-550-25
25 g
238.00
Description

Amoxicillin is an extended-spectrum ß-lactam antibiotic with a structure similar to that of ampicillin. It is effective against a variety of ß-lactamase negative bacteria including E. coli and various Streptococcus and Staphylococcus bacteria. It is also effective against a variety of other gram-negative and gram-positive bacteria.

Penicillins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a five-membered thiazolidine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Amoxicillin, Trihydrate

MOLECULAR BIOLOGY GRADE

Formula: C16H19N3O5S • 3H2O

MW: 419.45 g/mol

Storage/Handling: Store at 2-8°C.  Soluble in water.

PubChem Chemical ID: 62883

Product info

Catalog Id
Size
Price
a-552-1
1 g
96.00
a-552-5
5 g
160.00
Description

Amoxicillin/Clavulanate combines an extended-spectrum β-lactam antibiotic with a β-lactamase inhibitor. Amoxicillin is an extended-spectrum ß-lactam antibiotic with a structure similar to that of ampicillin. It is effective against a variety of ß-lactamase negative bacteria including E. coli and various Streptococcus and Staphylococcus bacteria; however, when combined with clavulanic acid, ß-lactamase enzymes are irreversibly inactivated. Consequently, amoxicillin/clavulanate is effective against ß-lactamase-negative and ß-lactamase-positive bacteria.

Penicillins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a five-membered thiazolidine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Amoxicillin/ Clavulanate
Augmentin® (by GSK)

MOLECULAR BIOLOGY GRADE

Formula: C24H27KN4O10S

MW: 602.66 g/mol

Storage/Handling: Store desiccated at 2-8°C.

PubChem Chemical ID: 23665637

Product info

Catalog Id
Size
Price
a-302-5
5 g
105.00
a-302-25
25 g
291.00
a-302-100
100 g
687.00
Description

Ampicillin is a member of the extended-spectrum β-lactam family and similar in structure to penicillin. It is used in the selection of antibiotic cell hybrids and has a high rate of action against many gram-negative bacterial strains. Ampicillin sodium targets non-ESBL (Extended Spectrum β-lactamase) bacteria including Staphylococcus and Streptococcus species and medically important enteric pathogens such as Shigella and Salmonella. It has been found to be effective against certain β-lactam sensitive VRE or vancomycin resistant Enterococcus species. Resistance to ampicillin is routinely utilized as a selectable marker to confirm successful cell transformation.

GoldBio’s anhydrous ampicillin is the most stable and pure form of ampicillin on the market and is suitable for the most sensitive research applications. It is sparingly soluble in water and freely soluble in 1 N NH4OH.

Product Specifications
Ampicillin, Anhydrous

Formula: C16H19N3O4S

MW: 349.40 g/mol

Storage/Handling: Store desiccated at 4°C.

Product info

Catalog Id
Size
Price
a-303-25
25 g
94.00
a-303-100
100 g
222.00
Description

Ampicillin is a member of the extended-spectrum β-lactam family and similar in structure to penicillin. It is used in the selection of antibiotic cell hybrids and has a high rate of action against many gram-negative bacterial strains. Ampicillin sodium targets non-ESBL (Extended Spectrum β-lactamase) bacteria including Staphylococcus and Streptococcus species and medically important enteric pathogens such as Shigella and Salmonella. It has been found to be effective against certain β-lactam sensitive VRE or vancomycin resistant Enterococcus species. Resistance to ampicillin is routinely utilized as a selectable marker to confirm successful cell transformation. Ampicillin trihydrate is slightly soluble in water and freely soluble in 1N HCl.

Product Specifications
Ampicillin Trihydrate

USP GRADE

Formula: C16H19N3O4S • 3H2O

MW: 403.45 g/mol

Storage/Handling: Store at 2-8°C. Store under inert gas. This product is light sensitive.

PubChem Chemical ID: 23565

Product info

Catalog Id
Size
Price
a-600-1
1 g
51.00
a-600-5
5 g
117.00
a-600-10
10 g
147.00
Description

Apramycin is an aminoglycoside antibiotic useful against gram-negative bacteria such as E. coli and Salmonella species. It is used to study antibiotic resistance and protein synthesis translocation inhibition. Apramycin sulfate is freely soluble.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Apramycin sulfate
Nebramycin II

MOLECULAR BIOLOGY GRADE

Formula: C21H41N5O11 • H2SO4

MW: 637.66 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 22008191

Product info

Catalog Id
Size
Price
a-900-25
25 mg
Description

Azithromycin is a broad-spectrum macrolide antibiotic similar in structure to erythromycin. It is effective against various gram-negative and gram-positive bacteria. It has also displayed efficacy against certain Mycoplasma species. Azithromycin also exhibits anti-inflammatory and immunosuppressive properties. Azithromycin dihydrate is slightly soluble in aqueous solution.

Macrolide antibiotics are composed of a macrocyclic lactone ring attached to one or more deoxy sugars. They inhibit bacterial protein synthesis by irreversibly binding the P site of the 50s ribosome, preventing peptide bond formation and translocation.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications

Azithromycin dihydrate

MOLECULAR BIOLOGY GRADE

Formula: C38H72N2O12 · 2H2O

MW: 785.01 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 3033819

Product info

Catalog Id
Size
Price
a-920-1
1 g
100.00
a-920-5
5 g
388.00
Description

Azlocillin is an extended-spectrum β-lactam antibiotic derived from ampicillin. It is useful against P. aeruginosa, E. coli, H. influenzae, and a variety of other gram-negative species. It has also been used to develop antibiotic counting techniques. Azlocillin sodium is freely soluble in aqueous solution.

β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Azlocillin Sodium Salt

MOLECULAR BIOLOGY GRADE

Formula: C20H22N5NaO6S

MW: 483.47 g/mol

Storage/Handling: Store at room temperature.

PubChem Chemical ID: 23684677

Product info

Catalog Id
Size
Price
a-930-500
500 mg
75.00
a-930-1
1 g
134.00
a-930-5
5 g
328.00
Description

Aztreonam is a monobactam β-lactam antibiotic whose structure contains only a single ring. Its unique ring structure makes it resistant to β-lactamases. Aztreonam is effective against gram-negative bacteria and is an economical antibiotic commonly used in plant tissue culture applications and against P. aeruginosa.

β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Aztreonam

MOLECULAR BIOLOGY GRADE

Formula: C13H17N5O8S2

MW: 435.43 g/mol

Storage/Handling: Store at 4°C.
Aztreonam is soluble in DMF and DMSO and is insoluble in water.

PubChem Chemical ID: 5742832

Product info

Catalog Id
Size
Price
a-940-100
100 mg
Description

Aztreonam solubilized is blend of aztreonam and 42-45% L-Arginine, making the product freely soluble in water. Aztreonam is a monobactam β-lactam antibiotic whose structure contains only a single ring. Its unique ring structure makes it resistant to β-lactamases. Aztreonam is effective against gram-negative bacteria and is an economical antibiotic commonly used in plant tissue culture applications and against P. aeruginosa.

β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Aztreonam

MOLECULAR BIOLOGY GRADE

Formula: C13H17N5O8S2

MW: 435.43 g/mol (active ingredient)

Storage/Handling: Store at 2-8 °C.

PubChem Chemical ID: 5742832

Product info

Catalog Id
Size
Price
b-070-1
1 g
38.00
b-070-5
5 g
62.00
b-070-10
10 g
84.00
b-070-25
25 g
138.00
b-070-50
50 g
216.00
b-070-100
100 g
380.00
Description

Bacitracin is a cyclic polypeptide antibiotic isolated from Bacillus subtilis. It is made up of a variety of antimicrobial peptide fractions including A, A1, B, B1, B2, C, D, E, F, G, and X. This standard grade product is a mixture of these fractions, with bacitracin A exhibiting the most potent antimicrobial activity. Bacitracins B1 and B2 exhibit about 90% of the antimicrobial activity of bacitracin A when together. Other forms of bacitracin have not been studied extensively, but may have negligible antimicrobial properties. Bacitracin is freely soluble in aqueous solution.

Bacitracin targets the cell wall of gram-positive organisms such as Streptococcus pyogenes and Staphylococcus aureus. Bacitracin also functions as a useful tool to distinguish between group A and group B β-hemolytic Streptococcus species, which are susceptible and resistant, respectively.

Bacitracin functions through inhibiting phosphorylation of bactoprenol, a step essential to synthesize peptidoglycan. Consequently, cell lysis occurs. Bacitracin resistance is conferred through a BcrABC transporter that pumps bacitracin out of cells or through BacA which allows phosphorylation of bactoprenol via an alternative biosynthesis pathway.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Bacitracin, USP Grade

Formula: C66H103N17O16S

MW: 1,422.69 g/mol

Storage/Handling: Store at 2-8 °C.

PubChem Chemical ID: 24891503

Product info

Catalog Id
Size
Price
b-800-25
25 mg
82.00
b-800-100
100 mg
264.00
b-800-500
500 mg
1,132.00
b-800-1
1 g
2,038.00
Description

Blasticidin S is an aminoacylnucleoside antibiotic isolated from Streptomyces griseochromogenes. It shows high efficacy against both eukaryotic and prokaryotic cells. Aside from its antimicrobial properties, blasticidin has displayed antiviral, antitumor, and antifungal properties and has been used as a selection agent. It has been used to select for cells containing the bls, bsr, or BSD resistance gene as well as HEK293-T cells and HEK-D5 cells. Additionally, blasticidin is effective in preventing cell culture contamination and studying protein synthesis.

Blasticidin S functions by inhibiting peptide bond formation at the ribosome. It blocks hydrolysis of peptidyl-tRNA due to the large ribosomal subunit’s increased affinity for tRNA.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.


Product Specifications
Blasticidin S HCl
Blasticidin S Hydrochloride

Formula: C17H26N8O5 HCl

MW: 458.9 g/mol

Storage/Handling: Store desiccated at -20°C.

PubChem Chemical ID 16760315

Product info

Catalog Id
Size
Price
c-530-500
500 mg
92.00
c-530-1
1 g
174.00
Description

Cefaclor is a second generation cephalosporin antibiotic isolated from the Acremonium fungus. It targets a wide variety of bacteria including Streptococcus pneumoniae and Haemophilus influenzae and a variety of other gram-negative and gram-positive bacteria. In addition, cefaclor has been useful in studying urinary tract and intra-abdominal infections and the mechanisms of renal transporters hOTA1, hPEPT1, and hPEPT2.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Cefaclor

MOLECULAR BIOLOGY GRADE

Formula: C15H14ClN3O4S

MW: 367.81 g/mol

Storage/Handling: Store at room temperature.

PubChem Chemical ID: 51039

Product info

Catalog Id
Size
Price
c-540-1
1 g
84.00
c-540-5
5 g
208.00
Description

Cefadroxil is a first generation cephalosporin antibiotic with a structure similar to that of cephalexin and cephradine. It targets a wide variety of bacterial species including Staphylococcus and Streptococcus species.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Cefadroxil

MOLECULAR BIOLOGY GRADE

Formula: C 16H17N3O5S

MW: 363.39 g/mol

Storage/Handling: Store in a dry and well-ventilated place.

PubChem Chemical ID: 47965