Aminoglycosides

Showing all 12 results

Product info

Catalog Id
Size
Price
a-530-1
1 g
90.00
a-530-5
5 g
244.00
Description

Amikacin hydrate is a broad-spectrum aminoglycoside antibiotic derived from kanamycin A. It is effective against gram-negative bacteria such as Pseudomonas aeruginosa and a variety of enteric species. It is also effective against Mycobacterium tuberculosis. Amikacin hydrate is freely soluble in aqueous solution.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Samples of microbes grown in the presence of a 30 μg amikacin disc with a zone of inhibition of <14 mm in diameter are considered resistant. Intermediate resistance zones of inhibition are typically 15 mm-16 mm in diameter.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Amikacin Hydrate

MOLECULAR BIOLOGY GRADE

Formula: C22H43N5O13 ∙ XH2O

MW: 585.60 g/mol (anhydrous)

Storage/Handling: Store desiccated at 2-8°C.

PubChem Chemical ID: 37768

Product info

Catalog Id
Size
Price
a-532-5
5 g
68.00
a-532-25
25 g
178.00
Description

Amikacin sulfate (disulfate) is a broad-spectrum aminoglycoside antibiotic derived from kanamycin A. It is effective against gram-negative bacteria such as Pseudomonas aeruginosa and a variety of enteric species. It is also effective against Mycobacterium tuberculosis. Amikacin sulfate is freely soluble in aqueous solution.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Amikacin Sulfate
Amikacin Disulfate

USP Grade

Formula: C22H43N5O13 ∙ 2H2SO4

MW: 781.76 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 19082597

Product info

Catalog Id
Size
Price
a-600-1
1 g
51.00
a-600-5
5 g
117.00
a-600-10
10 g
147.00
Description

Apramycin is an aminoglycoside antibiotic useful against gram-negative bacteria such as E. coli and Salmonella species. It is used to study antibiotic resistance and protein synthesis translocation inhibition. Apramycin sulfate is freely soluble.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Apramycin sulfate
Nebramycin II

MOLECULAR BIOLOGY GRADE

Formula: C21H41N5O11 • H2SO4

MW: 637.66 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 22008191

Product info

Catalog Id
Size
Price
d-450-25
25 g
140.00
d-450-100
100 g
351.00
Description

Dihydrostreptomycin is an aminoglycoside antibiotic targeting gram-positive bacteria and Mycobacterium species. It is a derivative of streptomycin and commonly used to study aminoglycoside uptake. Dihydrostreptomycin sulfate is freely soluble in aqueous solution.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Dihydrostreptomycin Sulfate

MOLECULAR BIOLOGY GRADE

Formula: C21H41N7O12 ∙ 1.5 H2SO4

MW: 730.71 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 6419912

Product info

Catalog Id
Size
Price
m-870-10
10 g
Description

Micronomicin sulfate is an aminoglycoside antibiotic effective against gram-negative bacteria. It is freely soluble in water.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Micronomicin Sulfate

MOLECULAR BIOLOGY GRADE

Formula: C20H41N5O7 ∙ H2SO4

MW: 561.65 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 171808

Product info

Catalog Id
Size
Price
n-620-5
5 g
30.00
n-620-10
10 g
44.00
n-620-25
25 g
68.00
n-620-100
100 g
118.00
n-620-500
500 g
558.00
Description

Neomycin is a broad-spectrum aminoglycoside antibiotic isolated from Streptomyces species. It targets gram-negative and gram-positive bacteria. Neomycin can also be used as a selection agent for prokaryotic cells transformed with the neo gene or NPT II resistance gene and to study toxic antibacterial side effects. In addition, neomycin is a calcium channel protein inhibitor and DNase I inhibitor. It can be used in a variety of cell culture applications.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

In addition to its use in antimicrobial susceptibility testing, neomycin sulfate is used for food testing in TSN agar to select for Clostridium perfringens. It inhibits growth of Enterobacteria and Clostridium bifermentans. Neomycin can be used to negatively select for plants transformed with plasmid containing Agrobacterium mediated transformation resistance and to cells containing pcDNA3 resistance plasmids.

Product Specifications
Neomycin Sulfate, USP Grade

Formula: C23H46N6O13 ∙ 3H2SO4

MW: 908.88 g/mol

Storage/Handling:Store at 2-8°C.

PubChem Chemical ID: 44134844

Product info

Catalog Id
Size
Price
n-630-5
5 mg
Description

Netilmicin sulfate is an aminoglycoside antibiotic similar to gentamicin and a derivative of sisomicin. It targets gram-negative bacteria as well as some gram-positive bacteria. Additionally, netilmicin has been used to study aminoglycoside resistance and susceptibility of Pseudomonas aeruginosa and Pseudomonas pseudomallei. It can be detected using liquid chromatography.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Netilmicin Sulfate

MOLECULAR BIOLOGY GRADE

Formula: C21H41N5O7 ∙ 2.5 H2SO4

MW: 720.75 g/mol

Storage/Handling: Store desiccated at 2-8°C.  This product is light sensitive and is hygroscopic.

PubChem Chem ID: 62115

Product info

Catalog Id
Size
Price
p-700-5
5 g
75.00
p-700-25
25 g
150.00
p-700-100
100 g
300.00
Description

Paromomycin is an aminoglycoside antibiotic isolated from Streptomyces rimosus. It targets a variety of gram-negative and gram-positive bacteria as well as several protozoan species. It displays activity similar to that of neomycin. Paromomycin sulfate is freely soluble.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Paromomycin Sulfate

Formula: C23H45N5O14 ∙ H2SO4

MW: 713.71 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 6420060

Product info

Catalog Id
Size
Price
r-400-250
250 mg
356.00
r-400-1
1 g
780.00
Description

Ribostamycin is an aminoglycoside antibiotic isolated from Streptomyces ribosifidicus. It is a broad-spectrum antibiotic targeting gram-positive and gram-negative bacteria. Ribostamycin has been used to in pharmacokinetic studies and to study kidney toxicity. It is also an inhibitor of protein disulfide isomerase (PDI).

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Ribostamycin Sulfate

MOLECULAR BIOLOGY GRADE

Formula: C17H34N4O10 ∙ H2SO4

MW: 552.55 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 18469537

Product info

Catalog Id
Size
Price
s-350-500
500 mg
177.00
s-350-1
1 g
310.00
Description

Sisomicin is a broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. It is related to gentamicin and targets gram-negative and gram-positive bacteria such as Klebsiella species, E. coli, P. aeruginosa, Enterobacter species, and Proteus species. It has been used in disk and tube dilution sensitivity assays.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Sisomicin Sulfate

MOLECULAR BIOLOGY GRADE

Formula: C19H37N5O7 ∙ 2.5H2SO4

MW: 692.72 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 20055515

Product info

Catalog Id
Size
Price
t-340-10
10 g
518.00
t-340-25
25 g
1,035.00
t-340-50
50 g
1,635.00
t-340-100g
100 g
2,607.00
Description

Tobramycin is an aminoglycoside antibiotic isolated from Streptomyces tenebrarius targeting gram-negative bacteria. It is often used to combat Pseudomonas species. It has been used to study cystic fibrosis and a variety of respiratory infections. Tobramycin is freely soluble in aqueous solution.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Tobramycin

MOLECULAR BIOLOGY GRADE

Formula: C18H37N5O9

MW: 467.51 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 36294

Product info

Catalog Id
Size
Price
t-341-1
1 g
123.00
t-341-5
5 g
462.00
t-341-10
10 g
771.00
Description

Tobramycin is an aminoglycoside antibiotic isolated from Streptomyces tenebrarius targeting gram-negative bacteria. It is often used to combat Pseudomonas species. It has been used to study cystic fibrosis and a variety of respiratory infections. Tobramycin sulfate is freely soluble in aqueous solution.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Tobramycin Sulfate

MOLECULAR BIOLOGY GRADE

Formula: C18H37N5O9 • H2SO4

MW: 565.59 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 54413