Carbapenems

Showing all 3 results

Product info

Catalog Id
Size
Price
f-350-50
50 mg
Description

Faropenem sodium is an ultra broad-spectrum β-lactam of the penem antibiotic class. It has been shown to be β-lactamase resistant and is especially effective against anaerobic bacteria responsible for oral infections, but targets a variety of gram-positive and gram-negative bacteria. Faropenem sodium is freely soluble in water.

β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Product Specifications
Faropenem Sodium

MOLECULAR BIOLOGY GRADE

Formula: C12H14NO5S ∙ Na

MW: 307.30 g/mol

Storage/Handling: Store at -20°C.

PubChem Chemical ID: 23663972

Product info

Catalog Id
Size
Price
i-600-10
10 g
184.00
i-600-25
25 g
416.00
i-600-50
50 g
742.00
i-600-100
100 g
1,342.00
Description

Imipenem is a carbapenem β-lactam antibiotic with a broad target spectrum. It has been shown to be effective against ESBL-producing Enterobacteriaceae and gram-negative and gram-positive organisms. Imipenem has also been shown to be effective against bacteria from the genus Burkholderia. Resistance to imipenem is conferred through the loss of the OprD porin protein.

β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Imipenem
Imipenem Monohydrate

MOLECULAR BIOLOGY GRADE

Formula: C12H17N3O4S ∙ H2O

MW: 317.36 g/mol

Storage/Handling: Store at -20°C.

PubChem Chemical ID: 5282372

Product info

Catalog Id
Size
Price
m-820-10
10 g
418.00
m-820-25
25 g
774.00
m-820-50
50 g
1,148.00
m-820-100
100 g
1,700.00
Description

Meropenem is a carbapenem β-lactam antibiotic. It targets gram-negative and gram-positive bacteria and displays high resistance to β-lactamase and kidney dehydropeptidase I activity. It is especially effective against bacteria responsible for causing meningitis and exhibits low toxicity when compared to similar antibiotics.

β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Meropenem

Formula: C17H25N3O5S • 3H2O

MW: 437.51 g/mol

Storage/Handling: Store desiccated at -20°C.

PubChem Chemical ID: 441130