Lincosamides

Showing all 2 results

Product info

Catalog Id
Size
Price
c-175-10
10 g
58.00
c-175-25
25 g
106.00
c-175-50
50 g
171.00
c-175-100
100 g
300.00
Description

Clindamycin is a lincosamide antibiotic primarily targeting gram-positive bacteria. It is also against anaerobic bacteria and protozoans such as Toxoplasma species.

Clindamycin binds the 50s ribosomal subunit preventing ribosomal translocation, resulting in inhibition of protein synthesis. It has been shown to exhibit synergistic properties when combined with vancomycin.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.


Product Specifications
Clindamycin Hydrochloride
Cleocin
Dalacin

MOLECULAR BIOLOGY GRADE

Formula: C 18H33ClN2O5S·HCl

MW: 461.44 g/mol

Storage/Handling: Store desiccated at -20°C. Soluble in water.

PubChem Chemical ID 16051951

Product info

Catalog Id
Size
Price
l-300-1
1 g
94.00
l-300-5
5 g
426.00
Description

Lincomycin HCl is a lincosamide antibiotic targeting gram positive and anaerobic bacteria as well as protozoans. It is commonly used to combat Staphylococcus and Streptococcus bacteria. Lincomycin HCl is freely soluble in aqueous solution.

Lincosamide antibiotics exhibit a mechanism similar to macrolide antibiotics. They work by binding the 50s ribosomal subunit and preventing peptide bond formation and translocation, essentially inhibiting protein synthesis. Resistance to lincomycin is conferred through mutations in the 50s ribosome.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Lincomycin HCl, USP Grade
Lincomycin Hydrochloride Monohydrate

Formula: C18H34N2O6S ∙ HCl ∙ H2O

MW: 461.01 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 71476