Biochemical Reagents
Showing 1–16 of 249 results
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(-)-Arctigenin is a dibenzylbutyrolactone ligand found in the root of Arctium lappa L. It is an inhibitor of topoisomerase II, viral integrase including HIV-1 integrase, PAC-1, TNF-alpha, and nitric oxide secretion. Additionally, (-)-arctigenin displays anti-oxidative, anti-inflammatory, and anti-cancer properties. (-)-Arctigenin has been used in research on cosmetics and pharmaceutical products.
Product Specifications:
(-)-Arctigenin
Formula: C21H24O6
MW: 372.41 g/mol
Storage/Handling: Store at -20°C.
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(+)-Bicuculline, a light-sensitive competitive GABAA and GABAA-gated chloride channel antagonist, functions in the biochemical field as a drug, CNS stimulator, convulsant and neurotransmitter. Its chemical identities are alkaloid and phthalide-isoquinoline compound. Extracted from plant alkaloid in 1932, this metabolite has been definitively located in Adlumia fungosa, Dicentra cucullaria, Fumariaceae and some species of Corydalis. (+)-Bicuculline acts primarily on ionotropic GABAA receptors but also blocks Ca2+-activated potassium channels and can act as an agrochemical.
As a poisonous neurotoxin, it affects nervous system responses associated with GABAA by binding to the receptors but not activating them, thus inhibiting the action of gamma-aminobutyric acid. This produces a powerful convulsive reaction mimicking epilepsy and has been used in lab studies of the condition. Administered with NMDA, it has induced paraplegia. Injection to the amygdala has also produced GABA-related anxiolytic effects on emotional states.
Product Specifications
(+)-Bicuculline
Bicuculline
Bicuculline+
Formula: C20H17NO6
MW: 367.35 g/mol
Storage/Handling: Store at 4°C.
PubChem Chemical ID: 10237
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Spartein is a class 1a antiarrhythmic agent sodium channel blocker from scotch broom. As a reagent it can be used to synthesize multiple different transformation catalysts and other molecules.
Product Specifications:
Spartein;
Pachycarpine;
Lupinidine
Formula: C15H26N2
MW: 234.38 g/mol
Storage/Handling: Store at 4°C.
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(S)-(+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid is more commonly known as naproxen. It is a non-steroidal anti-inflammatory agent and non-selective inhibitor of cyclooxygenase (COX-1 and COX-2). Naproxen has been shown to decrease production of thromboxane B2.
Product Specifications:
(S)-(+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
Naproxen
Formula: C14H14O3
MW: 230.26 g/mol
Storage/Handling: Store at room temperature.
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1-Benzoylacetone has been used as a 1,3-dicarbonyl compound model for studying keto-enol equilibria in aqueous acid and micellar solutions. Additionally, it has been studied using gas-phase electron diffraction and quantum chemistry.
Product Specifications
1-Benzoylacetone
Acetoacetophenone
1-Phenyl-1,3-butanedione
MOLECULAR BIOLOGY GRADE
Off-white to yellow crystalline powder
Formula: C10H10O2
MW: 162.19 g/mol
Storage/Handling: Store at -20°C.
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Product Specifications:
Formula: C59H97ClN2O4
MW: 933.87 g/mol
Storage/Handling: Store at room temperature.
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1,2-Benzoisothiazolin-3-one, sodium salt is an isothiazolinone biocine used in plants and as a preservative. Its mode of action is both fungicidal and microbicidal.
Product Specification:
1,2-Benzoisothiazolin-3-one, sodium salt
Formula: C7H4NNaOS
MW: 173.17 g/mol
Storage/Handling: Store at room temperature.
PubChem ID:13238744
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1,2-Di-O-octadecyl-rac-glycero-3-phosphocholine is an ether and glycerolipid containing a phosphocholine group. Phosphocholine is an intermediate form produced in tissues during the synthesis of phosphatidylcholine, selectively bonding with some proteins to suppress immune responses as a posttranslational modification. In addition, phosphocoline groups are partly responsible for the CRP recognition and immunologic response that removes damaged cells. 1,2-Di-O-octadecyl-rac-glycero-3-phosphocholine has therefore been used as a reagent and in studies of chemical-cell interactions and glycerophospholipid metabolism.
Product Specifications
1,2-Di-O-octadecyl-rac-glycero-3-phosphocholine
DL-alpha-Dioctadecyllecithin
1,2-Di-O-stearyl-rac-glycero-3-phosphocholine
2,3-Bis(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate
Formula: C44H92NO6P
MW: 762.17 g/mol
Storage/Handling: Store at -20°C.
PubChem Chemical ID: 179555
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1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine or DPPE is a phospholipid component of the cell membrane. It is used in membrane models and is part of the glycerophosphoethanolamine family. DPPE has been shown to cause competitive hydrogen bonding of amine groups with phosphate/carbonyl groups or water. Additionally, DPPE has been studied along with cholesterol, showing cholesterol’s ability to induce DPPE monolayer condensation when calcium ions are present.
Product Specifications
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
Dipalmitoyl-L-alpha-cephalin
1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine
Formula: C37H74NO8P
MW: 691.980 g/mol
Storage/Handling: Store desiccated at -20°C and protect from light.
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1,2-Octanediol has a variety of applications. It is used to improve HPLC separation of organic acids and bases and to synthesize halohydrin palmitates. Additionally, it is studied for its potential use as a pediculicide and has been shown to be effective against louse infestations.
Product Specifications:
1,2-Octanediol
Formula: C8H18O2
MW: 146.23 g/mol
Storage/Handling: Store at room temperature.
PubChem ID: 14231
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1,2,3,4-Tetra-O-acetyl-β-D-glucuronic acid methyl ester has been used in various biochemical studies. It has been used to study the potential of water-soluble camptothecin glucuronide derivatives as a cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy. Additionally, it has been used to assess the role of glycosylthio heterocycles in carbohydrates.
Product Specifications
1,2,3,4-Tetra-O-acetyl-β-D-glucuronic acid methyl ester;
beta-D-Glucopyranuronic acid, methyl ester, tetraacetate
Formula: C15H20O11
MW: 376.32 g/mol
Storage/Handling: Store at room temperature.
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1,3-Dilauroyl-glycero-2-phosphocholine is a glycerolipid and carboxylic ester used pharmaceutically. Glycerolipids are groups of fatty acids and glycerol joined with ester bonds. It can function as a human metabolite and acid. This substance also fits the chemical categories of phosphatidylcholine(1+) and quaternary ammonium ions.
Product Specifications
1,3-Dilauroyl-glycero-2-phosphocholine
1,3-Bis(dodecanoyloxy)-2-propanyl 2-(trimethylammonio)ethyl phosphate
Formula: C32H64NO8P
MW: 621.82 g/mol
Storage/Handling: Store desiccated at -20°C.
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