Vitamins

D-Biotin, also known as vitamin H or coenzyme R is a water-soluble member of the B vitamins (B7).

During fatty acid synthesis and gluconeogenesis, biotin acts as a flexible prosthetic group by allowing it to reach different enzymatic active sites.

Biotin can be used in cell culture media for its involvement in a number of cellular processes including gluconeogenesis, synthesis of fatty acids, and amino acids isoleucine and valine.

Product Specifications
D-Biotin
Vitamin H, Vitamin B₇

MOLECULAR BIOLOGY GRADE

Formula: C₁₀H₁₆N₂O₃S

MW: 244.31 g/mol

Storage/Handling: Store at 2-8 °C.

PubChem Chemical ID: 171548

Folic acid or vitamin B9 and the resulting metabolites are essential to a number of organisms. Folic acid is slightly soluble in aqueous solution and dissolves freely in dilute acids and alkaline solutions.

Cellular enzymes convert folic acid into dihydrolic acid, which is used as a precursor for a number of compounds, including tetrahydrofolate (THF). THF is involved in DNA repair and synthesis because of its role in purine synthesis.

Folic acid is frequently used in cell culture to provide tetrahydrofolates and other essential metabolites.

Product Specifications
Folic Acid
Vitamin B9

Formula: C₁₉H₁₉N₇ O₆

MW: 441.40 g/mol

Storage/Handling: Store at 4 °C.
This product is sensitive to light and heat.

PubChem Chemical ID: 6037

Nicotinamide is a metabolized amide form of vitamin B3. It is an anti-cancer agent and inhibitor of PARP-1, which is responsible for repairing DNA damage caused by chemotherapy. Nicotinamide is converted to nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP) for use in biological redox reactions. Additionally, nicotinamide is a nicotinamide phosphoribosyltransferase (NAMPT) substrate and anti-inflammatory agent.

Product Specifications
Nicotinamide, USP Grade
Vitamin B3

Formula: C₆H₆N₂O

MW: 122.12 g/mol

Storage/Handling: Store at 2-8°C.  This product is light sensitive.

PubChem Chemical ID: 936

Pyridoxine HCl is the primary component of the vitamin B6 and is involved in the metabolism and synthesis of a number of biological reactions. Pyridoxine is freely soluble in aqueous solution.

Pyridoxine serves as a precursor of pyridoxal-phosphate (PLP), a coenzyme for amino acid and nucleic acid metabolism and neurotransmitter synthesis.

Because of its role in essential cellular processes, pyridoxine is used in a number of plant and mammalian cell culture applications.

Product Specifications
Pyridoxine HCl
Vitamin B6

MOLECULAR BIOLOGY GRADE

Formula: C₈H₁₁NO₃ ∙ HCl

MW: 205.64 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 6019

Riboflavin is a member of the B vitamins (B2) and serves as a derivative of many flavoproteins in both plants and animals.

Riboflavin is a precursor of FAD (flavin adenine dinucleotide); a redox reaction cofactor, and FMN (flavin mononucleotide); an electron carrier involved in photosynthesis.

Riboflavin is used in plant cell culture because of its indirect role in photosynthesis.

Product Specifications
Riboflavin
Vitamin B2

MOLECULAR BIOLOGY GRADE

Formula: C₁₇H₂₀N₄O₆

MW: 376.36 g/mol

Storage/Handling: Store at 4°C. Protect from light.
Product is light sensitive.

PubChem Chemical ID: 493570

Thiamine is a member of the B vitamins (B1) and is commonly used in cell culture media.

Thiamine is involved in the synthesis of neurotransmitters acetylcholine and gamma-aminobutyric acid (GABA) in mammalian cells. In addition, thiamine serves as a precursor for thiamin tyrophosphate (TPP), a coenzyme involved in amino acid and carbohydrate synthesis.

Because of its active role in normal cell processes, thiamine HCl is commonly used as a cell culture supplement.

Product Specifications
Thiamine HCl
Vitamin B1 HCl

MOLECULAR BIOLOGY GRADE

Formula: C₁₂H₁₇ClN₄OS ∙ HCl

MW: 337.27 g/mol

Storage/Handling: Store desiccated at 2-8 °C. Product is light sensitive.
Hygroscopic.

PubChem Chemical ID: 6202