Growth Factors

Showing 1–16 of 342 results

Product info

Catalog Id
Size
Price
1140-01-10
10 μg
70.00
1140-01-50
50 μg
110.00
1140-01-1000
1000 μg
921.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption! 

Recombinant Human Fibroblast Growth Factor 1
FGF1, aFGF
Acidic FGF
Endothelial cell growth factor

FGF1 is a member of the Fibroblast Growth Factor family of proteins. Also called FGF-acidic or aFGF, FGF1 lacks signal peptides and is believed to be secreted by a nonclassical mechanism. It has been detected in large amounts in the brain and is expressed in hepatocyte cells, vascular smooth muscle cells, CNS neurons, skeletal muscle cells, fibroblasts, keratinocytes, endothelial cells, intestinal columnar epithelial cells, and pituitary basophils and acidophils. FGF1 exhibits considerable species cross-reactivity and stimulates the proliferation of cells of mesodermal origin, as well as many cells of neuroectodermal, ectodermal, and endodermal origin. It is most closely associated with FGF2 (bFGF) (see additional information).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~15.8 kDa (141 amino acids)

Purity: >95% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 0.5 ng/ml, corresponding to a specific activity of >2.0×106 IU/mg in the presence of 10 μg/ml of heparin.

Storage/Handling: Store desiccated at -20°C.

HGNC ID: 3665

NOT FOR HUMAN USE!

Cross-species homology
Percent Similarity
HuaFGF MuaFGF
HuaFGF *** 96.5
MuaFGF *** ***

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1340-01-10
10 μg
70.00
1340-01-50
50 μg
110.00
1340-01-1000
1000 μg
921.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Murine Fibroblast Growth Factor 1
FGF1, aFGF
Acidic FGF
Endothelial cell growth factor

FGF1 is a member of the Fibroblast Growth Factor family of proteins. Also called FGF-acidic or aFGF, FGF1 lacks signal peptides and is believed to be secreted by a nonclassical mechanism. It has been detected in large amounts in the brain and is expressed in hepatocyte cells, vascular smooth muscle cells, CNS neurons, skeletal muscle cells, fibroblasts, keratinocytes, endothelial cells, intestinal columnar epithelial cells and pituitary basophils and acidophils. FGF1 exhibits considerable species cross-reactivity and stimulates the proliferation of cells of mesodermal origin as well as many cells of neuroectodermal, ectodermal, and endodermal origin. It is most closely associated with FGF2 (bFGF) (see additional information).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~15.9 kDa (141 amino acids)

Purity: >95% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 0.2 ng/ml, corresponding to a specific activity of >5.0×106 IU/mg in the presence of 10 μg/ml of heparin.

Storage/Handling: Store desiccated at -20°C.

Mouse Genome Database ID: 95515

NOT FOR HUMAN USE!

Cross-species homology
Percent Similarity
HuaFGF MuaFGF
HuaFGF *** 96.5
MuaFGF *** ***

Additional resources for this protein may be found at:
OMIM

Note: 1000 µg volume may be delivered in multiple containers.

Product info

Catalog Id
Size
Price
1150-11-10
10 μg
70.00
1150-11-50
50 μg
110.00
1150-11-1000
1000 μg
1,318.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Amphiregulin
Amphiregulin B (AREGB)
Schwannoma-derived Growth Factor (SDGF)

AREG (Amphiregulin) is an EGF related growth factor containing 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. It was originally isolated from the MCF-7 human breast carcinoma cell line and is expressed in numerous carcinoma cell lines, as well as the epithelial cells of various human tissues including colon, stomach, breast, ovary, and kidney. AREG participates in autocrine signaling and binds to an EGF/TGF-α receptor, stimulating growth of keratinocytes, epithelial cells and some fibroblasts. It also inhibits the growth of certain carcinoma cell lines. It is synthesized as a transmembrane protein and the ectodomain is cleaved by a protease to release the mature protein. Overexpression of AREG produces a cutaneous phenotype resembling psoriasis.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source:Escherichia coli

MW: ~11.3 kDa (98 amino acids)

Purity: >95% by SDS-PAGE and HPLC analyses.

Storage/Handling: Store desiccated at -20°C.

HGNC: 651

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1640-02-10
10 μg
70.00
1640-02-50
50 μg
110.00
1640-02-1000
1000 μg
921.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Bovine Fibroblast Growth Factor 2
Fibroblast Growth Factor-basic
bFGF, FGF-2
Basic FGF

FGF2 is a member of the fibroblast growth factor family of proteins. It is often called FGF-basic or bFGF. FGF2 is a single-chain polypeptide growth factor that plays a significant role in wound healing, it is a potent inducer of angiogenesis and it is essential for the growth of many stem and progenitor cells. FGF2 shares a 55% amino acid residue identity with FGF1 and interacts with heparin sulfate with nanomolar affinity. It is a potent inducer of DNA synthesis in a variety of cell types. FGF2 activates mesenchymal splice variants of FGF receptors (c splice variants) and also activates FGF Receptor 1b, but has little activity against FGFR2b or FGFR3b. It is most closely associated with FGF1 (aFGF) (see additional information).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~16.5 kDa (147 amino acids)

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 0.1 ng/ml, corresponding to a specific activity of >1.0×107 IU/mg.

Purity: >97% by SDS-PAGE and HPLC analyses.

Storage/Handling: Store desiccated at -20°C.

NCBI: 281161

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1140-02-10
10 μg
70.00
1140-02-50
50 μg
110.00
1140-02-1000
1000 μg
879.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Fibroblast Growth Factor 2
Fibroblast Growth Factor-basic
bFGF, FGF-2
basic FGF

FGF2 is a member of the fibroblast growth factor family of proteins. It is often called FGF-basic or bFGF. FGF2 is a single-chain polypeptide growth factor that plays a significant role in wound healing, it is a potent inducer of angiogenesis and it is essential for the growth of many stem and progenitor cells. FGF2 shares a 55% amino acid residue identity with FGF1 and interacts with heparin sulfate with nanomolar affinity. It is a potent inducer of DNA synthesis in a variety of cell types. FGF2 activates mesenchymal splice variants of FGF receptors (c splice variants) and also activates FGF Receptor 1b, but has little activity against FGFR2b or FGFR3b. It is most closely associated with FGF1 (aFGF) (see additional information).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~16.5 kDa (147 amino acids)

Purity: >96% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 0.05 ng/ml, corresponding to a specific activity of >2.0×107 IU/mg.

Store desiccated at -20°C.

HGNC ID: 3676

NOT FOR HUMAN USE!

Cross-species homology
Percent Similarity
HubFGF MubFGF RtbFGF
HubFGF *** 97.3 96.6
MubFGF *** *** 98.6
RtbFGF *** *** ***

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1340-02-10
10 μg
70.00
1340-02-50
50 μg
110.00
1340-02-1000
1000 μg
862.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Murine Fibroblast Growth Factor 2
Fibroblast Growth Factor-basic
bFGF, FGF-2
basic FGF

FGF2 is a member of the Fibroblast Growth Factor family of proteins. It is often called FGF-basic or bFGF. FGF2 is a single-chain polypeptide growth factor that plays a significant role in wound healing, it is a potent inducer of angiogenesis and it is essential for the growth of many stem and progenitor cells. FGF2 shares a 55% amino acid residue identity with FGF1 and interacts with heparin sulfate with nanomolar affinity. It is a potent inducer of DNA synthesis in a variety of cell types. FGF2 activates mesenchymal splice variants of FGF receptors (c splice variants) and also activates FGF Receptor 1b, but has little activity against FGFR2b or FGFR3b. It is most closely associated with FGF1 (aFGF) (see additional information).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~16.2 kDa (146 amino acids)

Purity: >98% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 1.0 ng/ml, corresponding to a specific activity of >1.0×106 IU/mg.

Storage/Handling: Store desiccated at -20°C.

Mouse Genome Database ID: 95516

NOT FOR HUMAN USE!

Cross-species homology
Percent Similarity
HubFGF MubFGF RtbFGF
HubFGF *** 97.3 96.6
MubFGF *** *** 98.6
RtbFGF *** *** ***

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1540-02-10
10 μg
70.00
1540-02-50
50 μg
110.00
1540-02-1000
1000 μg
1,056.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Rat Fibroblast Growth Factor 2
Fibroblast Growth Factor-basic
bFGF, FGF-2
basic FGF

FGF2 is a member of the Fibroblast Growth Factor family of proteins. It is often called FGF-basic or bFGF. FGF2 is a single-chain polypeptide growth factor that plays a significant role in wound healing, it is a potent inducer of angiogenesis and it is essential for the growth of many stem and progenitor cells. FGF2 shares a 55% amino acid residue identity with FGF1 and interacts with heparin sulfate with nanomolar affinity. It is a potent inducer of DNA synthesis in a variety of cell types. FGF2 activates mesenchymal splice variants of FGF receptors (c splice variants) and also activates FGF Receptor 1b, but has little activity against FGFR2b or FGFR3b. It is most closely associated with FGF1 (aFGF) (see additional information).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~16.3 kDa (145 amino acids)

Purity: >98% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 0.2 ng/ml, corresponding to a specific activity of >5.0×106 IU/mg.

Storage/Handling: Store desiccated at -20°C.

Rat Genome Database ID: 2609

NOT FOR HUMAN USE!

Cross-species homology
Percent Similarity
HubFGF MubFGF RtbFGF
HubFGF *** 97.3 96.6
MubFGF *** *** 98.6
RtbFGF *** *** ***

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1180-02-2
2 μg
99.00
1180-02-10
10 μg
153.00
1180-02-100
100 μg
844.00
1180-02-1000
1000 μg
3,196.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Bone Morphogenetic Protein 2
BMP2
BMP2a

Bone Morphogenetic Proteins (BMPs) belong to the TGF-β (Transforming Growth Factor) superfamily of structurally related signaling proteins. BMP2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues; including the lung, spleen, brain, liver, prostate, ovary and small intestine. The functional form of BMP2 is a 26kDa protein composed of two identical 115 amino acid polypeptide chains linked by a single disulfide bond.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~26.0 kDa (2×115 amino acid)
(A homodimeric protein consisting of two 115 amino acid non-glycosylated polypeptide chains)

Purity: >95% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by inducing alkaline phosphatase production of murine ATDC5 cells is less than 200 ng/ml, corresponding to a specific activity of >5.0×103 IU/mg.

Store desiccated at -20°C.

HGNC ID: 1069

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Note: 1000 µg volume may be delivered in multiple containers.

Product info

Catalog Id
Size
Price
1180-04-2
2 μg
99.00
1180-04-10
10 μg
153.00
1180-04-1000
1000 μg
1,512.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Bone Morphogenetic Protein 4, Inactive Protein
BMP4
BMP2b
BMP2b1, BMP2b-1

Bone Morphogenetic Proteins (BMPs) belong to the TGF-β (Transforming Growth Factor) superfamily of structurally related signaling proteins. BMP4 is one of at least 15 structurally and functionally related BMPs originally identified as protein regulators of cartilage and bone formation. They have since been shown to be involved in embryogenesis and morphogenesis of various tissues and organs. BMPs have been shown to regulate the growth, differentiation, chemotaxis and apoptosis of a variety of cell types; including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. The active form of BMP4 can consist of a dimer of two identical proteins or a heterodimer of two related BMPs. BMP4 is essential for various processes in early development, beginning with gastrulation and mesoderm formation.

BMP4 Inactive protein is an excellent molecular marker for Western blotting and ELISA or as the molecular standard in detecting secreted BMP4 in reduced SDS-Page gels. It can also be used for preparing antibodies for the BMP4 monomer.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~13.0 kDa (117 amino acid)

Purity: >95% by SDS-PAGE and HPLC analyses

Biological Activity: Not biologically active.

Storage/Handling: Store desiccated at -20°C.

HGNC ID: 1071

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1180-07-2
2 μg
99.00
1180-07-10
10 μg
153.00
1180-07-1000
1000 μg
1,512.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Bone Morphogenetic Protein 7, Inactive Protein
BMP7
OP1
osteogenic protein 1

Bone Morphogenetic Proteins (BMPs) belong to the TGF-β (Transforming Growth Factor) superfamily of structurally related signaling proteins. BMP7 is one of at least 15 structurally and functionally related BMPs, originally identified as protein regulators of cartilage and bone formation which have since been shown to be involved in embryogenesis and morphogenesis of various tissues and organs. BMPs have been shown to regulate the growth, differentiation, chemotaxis and apoptosis of a variety of cell types; including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. The active form of BMP7 can consist of a dimer of two identical proteins or a heterodimer of two related BMPs. BMP7 is expressed highest in the kidneys and is genetically linked in mice to eye, skeletal and kidney development.

BMP7 Inactive protein is an excellent molecular marker for Western blotting and ELISA or as the molecular standard in detecting secreted BMP7 in reduced SDS-Page gels. It can also be used for preparing antibodies for the BMP7 monomer.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~15.6 kDa (139 amino acid)

Purity: >95% by SDS-PAGE and HPLC analyses

Biological Activity: Not biologically active.

Storage/Handling: Store desiccated at -20°C.

HGNC ID: 1074

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1170-12-5
5 μg
99.00
1170-12-20
20 μg
153.00
1170-12-1000
1000 μg
2,304.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Betacellulin (BTC)
BCN

BTC (Betacellulin) is an EGF related growth factor containing 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. It was originally isolated from the MCF-7 human breast carcinoma cell line and it is expressed in most tissues including kidney, uterus, liver and pancreas. BTC is also present in body fluids, including serum, milk, and colostrum. BTC is a ligand for the receptors erbB1 and erbB4. It is synthesized as a transmembrane protein and the ectodomain is cleaved by a protease to release the mature protein. BTC exhibits mitogenic activity for retinal pigment epithelial cells and vascular smooth muscle cells. It also exhibits growth-promoting activity that is similar to that of EGF.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~9.0 kDa (80 amino acids)

Purity: >98% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 0.05 ng/ml, corresponding to a specific activity of >2.0×107 IU/mg.

Storage/Handling: Store desiccated at -20°C.

HGNC: 1121

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1370-12-5
5 μg
99.00
1370-12-20
20 μg
153.00
1370-12-1000
1000 μg
2,304.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Murine Betacellulin (BTC)
BCN

BTC (Betacellulin) is an EGF related growth factor containing 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. It was originally isolated from the MCF-7 human breast carcinoma cell line and it is expressed in most tissues including kidney, uterus, liver and pancreas. BTC is also present in body fluids, including serum, milk, and colostrum. BTC is a ligand for the receptors erbB1 and erbB4. It is synthesized as a transmembrane protein and the ectodomain is cleaved by a protease to release the mature protein. BTC exhibits mitogenic activity for retinal pigment epithelial cells and vascular smooth muscle cells. It also exhibits growth-promoting activity that is similar to that of EGF.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~9.0 kDa (80 amino acids)

Purity: >96% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 0.01 ng/ml, corresponding to a specific activity of >1.0×108 IU/mg.

Storage/Handling: Store desiccated at -20°C.

MGI: 99439

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
2140-01-2
2 μg
99.00
2140-01-10
10 μg
153.00
2140-01-1000
1000 μg
2,304.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Chemokine (C-C motif) Ligand 1 (CCL1)
Inflammatory Cytokine I-309 (I309)
Small Inducible Cytokine Subfamily A Member 1 (SCYA1)
P500
Small Inducible Secreted, Epsilon (SISE)
T-Cell Activation (TCA-3)

CCL1 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed in and secreted from activated T-cells and it is chemotactic for monocytes, natural killer (NK) cells, and immature B-cells and dendritic cells. CCL1 has been shown to increase cytoplasmic calcium levels, protect T-cell lymphomas from apoptosis, and inhibit myeloid progenitors from proliferating. CCL1 is a ligand for CCR8 and is blocked by the viral CCR8 antagonist MC148R.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~8.6 kDa (74 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-100 ng/ml.

Storage/Handling: Store desiccated at -20°C.

HGNC: 10609

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
2140-11-5
5 μg
99.00
2140-11-20
20 μg
153.00
2140-11-1000
1000 μg
2,304.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Chemokine (C-C motif) Ligand 11 (CCL11)
Eotaxin, Eotaxin 1
Small Inducible Cytokine Subfamily A Member 11 (SCYA11)

CCL11 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed in dermal fibroblasts. Expression of CCL11 is induced by IL1A and TNFA and inhibited by IFNG. It is strongly and selectively chemotactic for eosinophils and induces a calcium flux response in eosinophils; thus it is involved in a variety of eosinophilic inflammatory diseases. CCL11 is a ligand for CCR1, CCR2, CCR3, CCR5, and ACKR2 (D6).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~8.4 kDa (74 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration of 0.1-10 ng/ml.

Storage/Handling: Store desiccated at -20°C.

HGNC: 10610

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
2340-11-5
5 μg
99.00
2340-11-20
20 μg
153.00
2340-11-1000
1000 μg
2,304.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Murine Chemokine (C-C motif) Ligand 11 (CCL11)
Eotaxin, Eotaxin 1
Small Inducible Cytokine Subfamily A Member 11 (SCYA11)

Murine CCL11 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed in fibroblasts, epithelial cells, smooth muscle cells, and dendritic cells. Expression of CCL11 is upregulated by several proinflammatory cytokines, including IL1A and TNFA, and is inhibited by IFNG. It is strongly and selectively chemotactic for eosinophils and induces a calcium flux response in eosinophils. CCL11 is involved in a variety of eosinophilic inflammatory diseases. CCL11 is a ligand primarily for CCR3, but also CCR1, CCR2, CCR5, and ACKR2 (D6).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~8.4 kDa (74 amino acids)

Purity: >96% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration of 100-1000 ng/ml.

Storage/Handling: Store desiccated at -20°C.

MGD: 103576

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
2540-11-5
5 μg
99.00
2540-11-20
20 μg
153.00
2540-11-1000
1000 μg
2,304.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Rat Chemokine (C-C motif) Ligand 11 (CCL11)
Eotaxin, Eotaxin 1
Small Inducible Cytokine Subfamily A Member 11 (SCYA11)

Rat CCL11 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed in fibroblasts, epithelial cells, smooth muscle cells, and dendritic cells. Expression of CCL11 is upregulated by several proinflammatory cytokines, including IL1A and TNFA, and is inhibited by IFNG. CCL11 is strongly and selectively chemotactic and activating for eosinophils and is involved in a variety of eosinophilic inflammatory diseases. It also plays a role in angiogenesis and tumor growth. CCL11 is a ligand primarily for CCR3, but also CCR1, CCR2, CCR5, and ACKR2 (D6).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~8.4 kDa (74 amino acids)

Purity: >96% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration of 100-1000 ng/ml.

Storage/Handling: Store desiccated at -20°C.

RGD: 3644

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM