Interferons

Showing all 12 results

Product info

Catalog Id
Size
Price
1160-01-20
20 μg
99.00
1160-01-100
100 μg
153.00
1160-01-1000
1000 μg
1,113.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Interferon, alpha 1A
IFNA1
Interferon, Leukocyte (IFL)
B-cell Interferon
Interferon-alphaD

Interferon alpha1 belongs to the type I interferon family and is encoded by the IFNA1 gene in humans. It is expressed in peripheral blood leukocytes and lymphoblastoid cells. It plays an important role in inducing non-specific resistance against a broad range of viral infections, and also affects cell proliferation and modulates immune responses. Interferon alpha proteins represent a group of related but distinct proteins that share over 95 % amino acid sequence homology. IFNA1 contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. IFNalpha1A differs from IFNalpha1B by having one alanine residue in a position where IFNalpha1B has a valine.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~19.5 kDa (167 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is >1.0×108 IU/mg.

Storage/Handling: Store desiccated at -20°C.

HGNC: 5417

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1160-02-2
2 μg
99.00
1160-02-10
10 μg
153.00
1160-02-1000
1000 μg
1,113.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Interferon, alpha 1B
IFNA1
Interferon, Leukocyte (IFL)
B-cell Interferon
Interferon-alphaD

Interferon alpha1 belongs to the type I interferon family and is encoded by the IFNA1 gene in humans. It is expressed in peripheral blood leukocytes and lymphoblastoid cells. It plays an important role in inducing non-specific resistance against a broad range of viral infections. It also affects cell proliferation and modulates immune responses. Interferon alpha proteins represent a group of related but distinct proteins that share over 95 % amino acid sequence homology. IFNA1 contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. IFNalpha1B differs from IFNalpha1A by having one valine residue in a position where IFNalpha1A has an alanine.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~19.5 kDa (167 amino acids)

Purity: >96% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is >1.0×108 IU/mg.

Storage/Handling: Store desiccated at -20°C.

HGNC: 5417

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1160-03-20
20 μg
99.00
1160-03-100
100 μg
153.00
1160-03-1000
1000 μg
502.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Interferon, alpha 2A
IFNA2
B-cell Interferon

Interferon alpha2 belongs to the type I interferon family and is encoded by the IFNA2 gene in humans. Like the other IFN-alpha proteins, it is expressed in leukocytes and plays an important role in inducing non-specific resistance against a broad range of viral infections. Recombinant IFN-alpha2A has been used to induce regression of corticosteroid-resistant hemangiomas in infancy. IFNA2 is one of 13 subtypes of interferon alpha found in humans, clustered on chromosome 9. It contains four highly conserved cysteine residues forming two disulfide bonds, one of which is necessary for biological activity.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~19.2 kDa (165 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is >1.0×108 IU/mg.

Storage/Handling: Store desiccated at -20°C.

HGNC: 5423

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1160-04e-20
20 μg
99.00
1160-04e-100
100 μg
153.00
1160-04e-1000
1000 μg
502.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Interferon, alpha 2B
IFNA2
B-cell Interferon

Interferon alpha2 belongs to the type I interferon family and is encoded by the IFNA2 gene in humans. Like the other IFN-alpha proteins, it is expressed in leukocytes and plays an important role in inducing non-specific resistance against a broad range of viral infections. Studies have shown the ability of recombinant IFN-alpha2B to decrease hepatic metastases from intraocular melanoma. It used to treat high-risk cutaneous melanomas, but is associated with many contraindications. IFNA2 is one of 13 subtypes of interferon alpha found in humans, clustered on chromosome 9. It contains four highly conserved cysteine residues forming two disulfide bonds, one of which is necessary for biological activity.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~19.4 kDa (166 amino acids)

Purity: >96% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is >1.0×108 IU/mg.

Storage/Handling: Store desiccated at -20°C.

HGNC: 5423

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1160-04y-20
20 μg
99.00
1160-04y-100
100 μg
153.00
1160-04y-1000
1000 μg
903.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Interferon, alpha 2B
IFNA2
B-cell Interferon

Interferon alpha2 belongs to the type I interferon family and is encoded by the IFNA2 gene in humans. Like the other IFN-alpha proteins, it is expressed in leukocytes and plays an important role in inducing non-specific resistance against a broad range of viral infections. Studies have shown the ability of recombinant IFN-alpha2B to decrease hepatic metastases from intraocular melanoma. It used to treat high-risk cutaneous melanomas, but is associated with many contraindications. IFNA2 is one of 13 subtypes of interferon alpha found in humans, clustered on chromosome 9. It contains four highly conserved cysteine residues forming two disulfide bonds, one of which is necessary for biological activity.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Saccharomyces cerevisiae

MW: ~19.4 kDa (166 amino acids)

Purity: >98% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is >1.6×108 IU/mg.

Storage/Handling: Store desiccated at -20°C.

HGNC: 5423

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1160-05-2
2 μg
99.00
1160-05-10
10 μg
153.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Interferon, beta 1B
IFNB1
Interferon, Fibroblast (IFF)
Beta-Interferon
IFB

Interferon beta 1 belongs to the type I interferon family and is encoded by the IFNB1 gene in humans. It is produced by many types of cells including fibroblasts, osteoblasts, lymphocytes, macrophages, endothelial cells, and others. IFNB1 plays an important role in inducing non-specific resistance against a broad range of viral infections. The IFN-beta family has 2 subtypes, which are IFN-beta1 (IFNB1) and IFN-beta3 (IFNB3) (a gene designated IFN-beta2 is actually IL-6). IFN-beta1 is used as a treatment for multiple sclerosis as it reduces the relapse rate.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~20.0 kDa (166 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is >3.0×107 IU/mg.

Storage/Handling: Store desiccated at -20°C.

HGNC: 5434

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1460-06-20
20 μg
99.00
1460-06-100
100 μg
153.00
1460-06-1000
1000 μg
944.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Canine Interferon Gamma
IFNG
IFG
IFN, Immune (IFI)

Interferon gamma is the only type II interferon and binds to the heterodimeric IFNGR that consists of two chains, IFNGR1 and IFNGR2. This interaction activates the JAK-STAT pathway. IFNG is produced primarily by T-lymphocytes and natural killer (NK) cells. It is critical for innate and adaptive immunity against viral and intracellular bacterial infections. This is due partly to its ability to inhibit viral replication directly, but also due to its immunostimulatory and immunomodulatory effects. IFNG induces the production of cytokines and upregulates the expression of class I and II MHC antigens, Fc receptors, and leukocyte adhesion molecules. It modulates macrophage effector functions, influences isotype switching, and potentiates the secretion of immunoglobulins by B cells. Additionally, IFNG augments TH1 cell expansion and may be required for TH1 cell differentiation.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~16.9 kDa (143 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using A-72 canine fibroma cells infected with vesicular stomatitis virus (VSV) is less than 2.0 ng/ml, corresponding to a specific activity of >5.0×105 IU/mg.

Storage/Handling: Store desiccated at -20°C.

NCBI: 403801

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1060-06-20
20 μg
99.00
1060-06-100
100 μg
153.00
1060-06-1000
1000 μg
963.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Equine Interferon Gamma
IFNG
IFG
IFN, Immune (IFI)

Interferon gamma is the only type II interferon and binds to the heterodimeric IFNGR that consists of two chains, IFNGR1 and IFNGR2. This interaction activates the JAK-STAT pathway. IFNG is produced primarily by T-lymphocytes and natural killer (NK) cells. It is critical for innate and adaptive immunity against viral and intracellular bacterial infections. This is due partly to its ability to inhibit viral replication directly, but also due to its immunostimulatory and immunomodulatory effects. IFNG induces the production of cytokines and upregulates the expression of class I and II MHC antigens, Fc receptors, and leukocyte adhesion molecules. It modulates macrophage effector functions, influences isotype switching, and potentiates the secretion of immunoglobulins by B cells. Additionally, IFNG augments TH1 cell expansion and may be required for TH1 cell differentiation.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~16.7 kDa (143 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using human HeLa cells infected with encephalomyocarditis (EMC) virus is less than 10.0 ng/ml, corresponding to a specific activity of >1.0×105 IU/mg.

Storage/Handling: Store desiccated at -20°C.

NCBI: 100034181

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1160-06-20
20 μg
99.00
1160-06-100
100 μg
153.00
1160-06-1000
1000 μg
906.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Interferon Gamma
IFNG
IFG
IFN, Immune (IFI)

Interferon gamma is the only type II interferon found in humans and binds to the heterodimeric IFNGR that consists of two chains, IFNGR1 and IFNGR2. This interaction activates the JAK-STAT pathway. IFNG is produced primarily by T-lymphocytes and natural killer (NK) cells. It is critical for innate and adaptive immunity against viral and intracellular bacterial infections. This is partly due to its ability to inhibit viral replication directly, but also due to its immunostimulatory and immunomodulatory effects. IFNG induces the production of cytokines and upregulates the expression of class I and II MHC antigens, Fc receptors, and leukocyte adhesion molecules. It modulates macrophage effector functions, influences isotype switching, and potentiates the secretion of immunoglobulins by B cells. Additionally, IFNG augments TH1 cell expansion and may be required for TH1 cell differentiation.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~16.9 kDa (144 amino acids)

Purity: >98% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using HT-29 cells is less than 0.05 ng/ml, corresponding to a specific activity of >2.0×107 IU/mg.

Storage/Handling: Store desiccated at -20°C.

HGNC: 5438

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1360-06-20
20 μg
99.00
1360-06-100
100 μg
153.00
1360-06-1000
1000 μg
963.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Murine Interferon Gamma
IFNG
IFG
IFN, Immune (IFI)

Interferon gamma is the only type II interferon and binds to the heterodimeric IFNGR that consists of two chains, IFNGR1 and IFNGR2. This interaction activates the JAK-STAT pathway. IFNG is produced primarily by T-lymphocytes and natural killer (NK) cells. It is critical for innate and adaptive immunity against viral and intracellular bacterial infections. This is due partly to its ability to inhibit viral replication directly, but also due to its immunostimulatory and immunomodulatory effects. IFNG induces the production of cytokines and upregulates the expression of class I and II MHC antigens, Fc receptors, and leukocyte adhesion molecules. It modulates macrophage effector functions, influences isotype switching, and potentiates the secretion of immunoglobulins by B cells. Additionally, IFNG augments TH1 cell expansion and may be required for TH1 cell differentiation.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~15.5 kDa (144 amino acids)

Purity: >96% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using murine L929 cells infected with encephalomyocarditis (EMC) virus is less than 0.8 ng/ml, corresponding to a specific activity of >1.3×106 IU/mg.

Storage/Handling: Store desiccated at -20°C.

Mouse Genome Database ID: 107656

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1560-06-20
20 μg
99.00
1560-06-100
100 μg
153.00
1560-06-1000
1000 μg
1,026.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Rat Interferon Gamma
IFNG
IFG
IFN, Immune (IFI)

Interferon gamma is the only type II interferon and binds to the heterodimeric IFNGR that consists of two chains, IFNGR1 and IFNGR2. This interaction activates the JAK-STAT pathway. IFNG is produced primarily by T-lymphocytes and natural killer (NK) cells. It is critical for innate and adaptive immunity against viral and intracellular bacterial infections. This is due partly to its ability to inhibit viral replication directly, but also due to its immunostimulatory and immunomodulatory effects. IFNG induces the production of cytokines and upregulates the expression of class I and II MHC antigens, Fc receptors, and leukocyte adhesion molecules. It modulates macrophage effector functions, influences isotype switching, and potentiates the secretion of immunoglobulins by B cells. Additionally, IFNG augments TH1 cell expansion and may be required for TH1 cell differentiation.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~15.5 kDa (134 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using murine L929 cells infected with encephalomyocarditis (EMC) virus is less than 0.1 ng/ml, corresponding to a specific activity of >1.0×107 IU/mg.

Storage/Handling: Store desiccated at -20°C.

Rat Genome Database ID: 2866

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1160-09-20
20 μg
99.00
1160-09-100
100 μg
153.00
1160-09-1000
1000 μg
1,026.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Interferon Omega 1
IFNW1
IFN-Alpha-like

Interferon omega 1 is a member of the type I family of interferons. It is the only functional interferon omega gene in humans; many pseudogenes of interferon omega exist in humans, some of which are functional in non-primate placental mammals. Expression of IFNW1 is seen in leukocytes in response to viral infection or treatment with double-stranded RNA. It stimulates NK cell activity, enhances expression of major histocompatibility complex class I antigens, and inhibits proliferation of lymphocytes stimulated with mitogens or allogeneic cells. It also inhibits proliferation of a variety of tumor cell lines in vitro.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~20.0 kDa (172 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human TF-1 cells is less than 0.01 ng/ml, corresponding to a specific activity of >1.0×108 IU/mg.

Storage/Handling: Store desiccated at -20°C.

HGNC: 5448

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM