Peptide Hormones

Showing 1–16 of 24 results

Product info

Catalog Id
Size
Price
1150-18-5
5 μg
117.00
1150-18-20
20 μg
172.00
1150-18-1000
1000 μg
2,772.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Cysteine-rich Angiogenic Inducer 61
CCN1
GIG1
IGFBP10

Cysteine-rich angiogenic inducer 61 (Cyr61) is a dynamically expressed, multifunctional matricellular protein of the CCN family encoded by the Cyr61 gene. Cyr61 is critical for cardiovascular development during embryogenesis and regulates inflammation, wound healing and fibrogenesis in the adult. It is involved in cell adhesion, cell migration, cell proliferation, and cell differentiation. Cyr61 consists of four domains: an IGFBP domain, a VWF type C domain, a TSP type I domain, and a cysteine knot domain.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source:Escherichia coli

MW: ~39.4 kDa (357 amino acids)

Purity: >95% by SDS-PAGE and HPLC analyses.

Storage/Handling: Store desiccated at -20°C.

HGNC: 2654

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
3110-01-20
20 μg
Description

Product info

Catalog Id
Size
Price
1150-01b-20
20 μg
117.00
1150-01b-100
100 μg
172.00
1150-01b-1000
1000 μg
208.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant HumanDES1-3 Insulin-like Growth Factor 1 (rHuDES(1-3) IGF1)
Truncated IGF1
DES IGF-1

IGF1 belongs to the insulin gene family. It is a mitogenic polypeptide growth factor that stimulates the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF1 DES is a truncated variant of human IGF1 with the tripeptide Gly-Pro-Glu absent from the N-terminus. It has been isolated from bovine colostrum, human brain, and porcine uterus. The IGF1 DES is believed to result from post-translational cleavage of IGF1 via protease activity. It is about 10-fold more potent than IGF1 at stimulating hypertrophy and proliferation of cultured cells, a consequence of much reduced binding to IGF-binding proteins, which is in turn caused by the absence of the glutamate at position 3. Clinical opportunities for IGF1-DES have not yet been evaluated, but could apply in catabolic states as well as for the treatment of inflammatory bowel diseases.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~7.4 kDa (67 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses.

Storage/Handling:Store desiccated at -20°C.

HGNC: 5464 (IGF)

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1150-01n-10
10 μg
117.00
1150-01n-50
50 μg
172.00
1150-01n-1000
1000 μg
1,083.00
1150-01n-250
432.00
1150-01n-500
660.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Insulin-like Growth Factor-1, 15N Stable Isotope Labeled
Somatomedin C, 15N Stable Isotope Labeled

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors, predominantly produced in the liver, that stimulate the proliferation and survival of various cell types, including muscle, bone and cartilage tissue in vitro. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGFIR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant human IGF1 is a globular protein containing 70 amino acids and 3 intra-molecular disulfide bonds. This particular product has been labeled with the stable 15N isotope to help track its activity.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~7.7 kDa (70 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses.

Storage/Handling:Store desiccated at -20°C.

HGNC: 5464

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1150-01-100
100 μg
117.00
1150-01-500
500 μg
172.00
1150-01-1000
1000 μg
208.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Insulin-like Growth Factor 1
IGF1
Somatomedin C

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone and cartilage tissue in vitro. They are predominantly produced in the liver. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGF IR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant human IGF1 is a globular protein containing 70 amino acids, and 3 intra-molecular disulfide bonds.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~7.6 kDa (70 amino acid)

Purity: >95% by SDS-PAGE and HPLC analyses

Storage/Handling: Store desiccated at -20°C.

HGNC ID: 5464

NOT FOR HUMAN USE!

Cross-species homology


Percent Similarity

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1150-03-1
1 mg
184.00
1150-03-5
5 mg
558.00
1150-03-50
50 mg
2,798.00
1150-03-20
1,276.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human LR3 Insulin-like Growth Factor-1
LR3-IGF1

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors, predominantly produced in the liver, that stimulate the proliferation and survival of various cell types, including muscle, bone and cartilage tissue in vitro. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGF IR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant human IGF1 is a globular protein containing 70 amino acids and 3 intra-molecular disulfide bonds.

The LR3 IGF1 has a substitution of arginine for the glutamic acid at position 3 of human IGF1 and an extension of 13 amino acid residues. This change of sequence causes it to have a much longer half-life and is specifically designed and manufactured for mammalian cell culture to support large-scale manufacturing of recombinant biopharmaceuticals.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~9.1 kDa (83 amino acids)

Purity: >98% by SDS-PAGE analysis
>90% by RP-HPLC analysis

Storage/Handling: Store desiccated at -20°C.

HGNC (IGF1): 5464

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1150-03u-100
100 μg
100.00
1150-03u-1000
1000 μg
202.00
1150-03u-10
10 mg
1,012.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human LR3 Insulin-like Growth Factor-1
LR3-IGF1

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors, predominantly produced in the liver, that stimulate the proliferation and survival of various cell types, including muscle, bone and cartilage tissue in vitro. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGF IR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant human IGF1 is a globular protein containing 70 amino acids and 3 intra-molecular disulfide bonds.

The LR3 IGF1 has a substitution of arginine for the glutamic acid at position 3 of human IGF1 and an extension of 13 amino acid residues. This change of sequence causes it to have a much longer half-life and is specifically designed and manufactured for mammalian cell culture to support large-scale manufacturing of recombinant biopharmaceuticals.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW:~9.1 kDa (83 amino acids)

Purity: >98% by SDS-PAGE analysis
>95% by RP-HPLC analysis

Storage/Handling:Store desiccated at -20°C.

HGNC (IGF1): 5464

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1350-01-10
10 μg
117.00
1350-01-50
50 μg
172.00
1350-01-1000
1000 μg
1,142.00
1350-01-250
423.00
1350-01-500
642.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Murine Insulin-like Growth Factor-1
IGF-1
Somatomedin C

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors, predominantly produced in the liver, that stimulate the proliferation and survival of various cell types, including muscle, bone and cartilage tissue in vitro. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGFIR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant murine IGF1 is a globular protein containing 70 amino acids, and 3 intra-molecular disulfide bonds.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source:Escherichia coli

MW: ~7.7 kDa (70 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses.

Storage/Handling: Store desiccated at -20°C.

Mouse Genome Database ID: 96432

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1550-01-10
10 μg
117.00
1550-01-50
50 μg
172.00
1550-01-1000
1000 μg
1,206.00
1550-01-250
448.00
1550-01-500
674.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Rat Insulin-like Growth Factor 1
IGF1
Somatomedin

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. They are predominantly produced in the liver. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGF IR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant human IGF1 is a globular protein containing 70 amino acids, and 3 intra-molecular disulfide bonds.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~7.7 kDa (70 amino acid)

Purity: >97% by SDS-PAGE and HPLC analyses

Storage/Handling: Store desiccated at -20°C.

Rat Genome Database ID: 2868

NOT FOR HUMAN USE!

Cross-species homology


Percent Similarity

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1150-01b3-5
5 μg
117.00
1150-01b3-25
25 μg
172.00
1150-01b3-1000
1000 μg
2,220.00
1150-01b3-250
896.00
1150-01b3-500
1,390.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Insulin-like Growth Factor Binding Protein 3
IGF-BP3

Insulin-like Growth Factor-Binding Protein 3 (IGFBP3) belongs to the IGFBP family, which are all proteins with conserved cysteine residues, an IGFBP domain, and a thyroglobulin type-I domain. IGFBP3 is expressed by most tissues and is the most abundant IGFBP protein. It has higher levels of expression during postnatal life, which peak during puberty. The expression of IGFBP3 in fibroblasts is stimulated by a number of mitogenic growth factors. The protein forms a ternary complex with IGFI or IGFII, and an acid-labile subunit, causing it to circulate in the plasma. As this complex, it prolongs the half-life of IGFs and alters their interaction with cell surface receptors. Decreased plasma levels of IGFBP3 often happen during the progression of prostate cancer from benign to metastatic disease.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~28.8 kDa (264 amino acids)

Purity: >98% by SDS-PAGE and HPLC analyses.

Storage/Handling:Store desiccated at -20°C.

HGNC: 5472

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1150-01b7-5
5 μg
117.00
1150-01b7-25
25 μg
172.00
1150-01b7-1000
1000 μg
2,220.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant HumanInsulin-like Growth Factor Binding Protein 7
MAC25
IGF Binding Protein-Related Protein 1 (IGFBPrP1)
Tumor-derived Adhesion Factor (TAF)
Prostacyclin Stimulating Factor (PSF)
Angiomodulin (AGM)
FSTL2
IBP-7

IGFBP7 belongs to the superfamily of insulin-like growth factor (IGF) binding proteins and is encoded by the IGFBP7 gene in human. It is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. IGFBP7 includes conserved cysteine residues. IGFBP7 modulates the biological activities of IGF proteins. It also suppresses growth and colony formation of prostate and breast cancer cell lines. Above all, IGFBP7 is a very important factor in skeletal myogenesis. Human IGFBP7 cDNA encodes a 282 amino acid (a.a.) residue precursor protein with a putative 26 a.a. signal peptide.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW:~26.4 kDa (256 amino acids)

Purity:>95% by SDS-PAGE and HPLC analyses.

Storage/Handling:Store desiccated at -20°C.

HGNC: 5476

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
3110-06-200
200 μg
117.00
3110-06-1000
1000 μg
172.00
3110-06-5000
5000 μg
432.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Leptin (LEP)
Homolog of Murine Obesity (OB, OBS)

Human Leptin is a hormone expressed and secreted primarily by adipose tissues, though also produced by a variety of other cells at lower levels. It is a ligand for the leptin receptor (LEPR) that is expressed at highest levels in the hypothalamus. Leptin’s primary role is in the regulation of energy balance in the body, stimulating energy expenditure while inhibiting hunger. It inhibits the activity of neuropeptide Y and downregulates the expression of endocannabinoids, while upregulating expression of α-melanocyte-stimulating hormone. Obesity is correlated with a receptor desensitization to leptin that leaves the eater hungry despite high energy stores. Leptin also plays a role in hematopoiesis, angiogenesis, ossification, inflammation, and immune responses.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~16.0 kDa (146 amino acids)

Purity: >97% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human Leptin R transfected BaF3 murine proB cells is less than 2 ng/ml, corresponding to a specific activity of >5.0×105 IU/mg.

Storage/Handling: Store desiccated at -20°C.

HGNC: 6553

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1150-01b9-5
5 μg
117.00
1150-01b9-20
20 μg
172.00
1150-01b9-1000
1000 μg
2,772.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Nephroblastoma-overexpressed Gene Protein Homolog
Nephroblasta Overexpressed
CCN3
IGF Binding Protein-Related Protein 3 (IGFBPrP3)
IGFBP9
NOVH


NOV is a dynamically expressed, multifunctional matricellular protein of the CCN (CTGF/CYR61/NOV) family encoded by the NOV gene. It is expressed in certain tumors, including Wilm’s tumor and most nephroblastomas. Expression of NOV has been reported to reduce tumorgenicity and reduce proliferation of certain cancer cell lines. It has also been shown to induce angiogenesis in endothelial cells and stimulate cell migration in many mesenchymal cell types. Recombinant human NOV is a 36.2 kDa protein containing 331 amino acid residues and it shares 80% and 81% amino acid identity with rat and murine NOV.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source:Escherichia coli

MW: ~36.2 kDa (331 amino acids)

Purity: >95% by SDS-PAGE and HPLC analyses.

Storage/Handling:Store desiccated at -20°C.

HGNC:7885

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
1350-01b9-5
5 μg
117.00
1350-01b9-20
20 μg
172.00
1350-01b9-1000
1000 μg
2,772.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Murine Nephroblastoma-overexpressed Gene Protein Homolog
Nephroblasta Overexpressed
CCN3
IGF Binding Protein-Related Protein 3 (IGFBPrP3)
IGFBP9
NOVH

NOV is a dynamically expressed, multifunctional matricellular protein of the CCN (CTGF/CYR61/NOV) family encoded by the NOV gene. It is expressed in certain tumors, including Wilm’s tumor and most nephroblastomas. Expression of NOV has been reported to reduce tumorgenicity and reduce proliferation of certain cancer cell lines. It has also been shown to induce angiogenesis in endothelial cells and stimulate cell migration in many mesenchymal cell types. Recombinant murine NOV is a 36.4 kDa protein containing 333 amino acid residues and it shares 92% and 82% amino acid identity with rat and human NOV.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source:Escherichia coli

MW: ~36.4 kDa (333 amino acids)

Purity: >95% by SDS-PAGE and HPLC analyses.

Storage/Handling: Store desiccated at -20°C.

Mouse Genome Database ID: 109185

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
3310-10-10
10 μg
117.00
3310-10-50
50 μg
172.00
3310-10-1000
1000 μg
1,206.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Murine Prolactin (PRL)
Lactogenic Hormone
Lactotropin
Mammotropin
Luteotropin

Murine Prolactin (PRL) is a peptide hormone that is secreted most notably from the pituitary gland where it acts in an endocrine fashion, but also from extra pituitary regions where it acts in an autocrine or paracrine fashion. PRL serves as a ligand for the prolactin receptor, PRLR. It is listed as having over 300 separate functions and is involved in more processes than any other pituitary hormone. PRL is most commonly known for its lactation stimulating effect, but also plays a role in reproductive behavior, homeostasis of electrolytes, growth and development, regulation of metabolism, immune system regulation, angiogenesis, and survival of cancer cells. Homozygous female knock-out mice lacking expression of PRL become infertile, whereas homozygous males were fully fertile.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~22.4 kDa (197 amino acids)

Purity: >98% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat Nb2-11 cells is less than 1.0 ng/ml, corresponding to a specific activity of >1.0×106 IU/mg.

Storage/Handling: Store desiccated at -20°C.

MGI: 97762

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM

Product info

Catalog Id
Size
Price
3510-10-10
10 μg
117.00
3510-10-50
50 μg
172.00
3510-10-1000
1000 μg
1,206.00
Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Rat Prolactin (PRL)
Lactogenic Hormone
Lactotropin
Mammotropin
Luteotropin

Rat Prolactin (PRL) is a peptide hormone that is secreted most notably from the pituitary gland where it acts in an endocrine fashion, but also from extra pituitary regions where it acts in an autocrine or paracrine fashion. It is listed as having over 300 separate functions and is involved in more processes than any other pituitary hormone. PRL is most commonly known for its lactation stimulating effect, but also plays a role in reproductive behavior, homeostasis of electrolytes, growth and development, regulation of metabolism, immune system regulation, angiogenesis, and survival of cancer cells. PRL acts as a ligand for the prolactin receptor, PRLR.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~22.6 kDa (197 amino acids)

Purity: >98% by SDS-PAGE and HPLC analyses

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat Nb2-11 cells is less than 1.0 ng/ml, corresponding to a specific activity of >1.0×106 IU/mg.

Storage/Handling: Store desiccated at -20°C.

RGD: 3403

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:
OMIM