Albendazole

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Description

Albendazole is a benzimidazole derivative typically used as a comprehensive antiparasitic belonging to the anthelminthic group and works by disrupting microtubule formation. Microtubule disruption diminishes glucose transport which increases glycogen catabolism. Eventually, this net loss of energy results in tissue death.

The resulting tissue death caused by microtubule formation is a sought after mechanism in oncology research. In vitro research of albendazole on HNSCC (head and neck squamous cancer cells) had shown cell cycle arrest in G2/M stage, resulting in apoptosis. Disruption of microtubule formation also prevented malignant cell migration.

Product Specifications
Albendazole
Methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl) carbamate

Formula: C12H15N3O2S

MW: 265.33 g/mol

Storage/Handling: Store at room temperature.

PubChem Chemical ID: 2082

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

Additional information

CatalogID

A-210-10, A-210-100

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