Ampho99 is the purest form of amphotericin B available and should be used for the most sensitive applications. In general, GoldBio’s USP Grade amphotericin B will not adversely affect your cells and is suitable for most experiments.
Amphotericin B is a polyene antifungal isolated from Streptomyces species. While it has been suggested that Amphotericin B interacts with ergosterol of the fungal cell membrane leading to an altered cell membrane permeability and death, more recent studies show that the mechanism behind amphotericin B’s fungicidal activity is more complex. It is most effective against fungi and yeast and is often used against opportunistic fungal infections and leishmaniasis. Additionally, amphotericin B can be used to prevent growth of F. oxysporum in chickpea and P. triticina in wheat. It is soluble in acidic and basic conditions.
MW: 924.08 g/mol
Storage/Handling: Store at 2-8°C. Soluble in DMSO or DMF. This product is light sensitive.
PubChem Chemical ID: 5280965
A-562-1, A-562-250, A-562-500