Anisomycin

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Description

Anisomycin is an antifungal produced by Streptomyces griseolus. It functions by inhibiting protein synthesis in certain eukaryotic cells. Anisomycin inhibits peptidyl transferase activity in the 60s subunit of the 80s ribosome.

Anisomycin has been shown to promote apoptosis in promyelocytic leukemia cells, Jurkat cells, ventricular monocytes, and colon adenocarcinoma cells. Additionally, anisomycin is a JNK agonist and activates MAP kinases. It is a useful antiprotozoal agent.

Product Specifications
Anisomycin

MOLECULAR BIOLOGY GRADE

Formula: C14H19NO4

MW: 265.30 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 253602

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

Additional information

CatalogID

A-580-10, A-580-100, A-580-25, A-580-50, A-580-500

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