Description
Description | Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. |
Targets&IC50 | GABAA receptor:2 μM |
Source |
Synonyms | (+)-Bicuculline, d-Bicuculline |
Molecular Weight |
367.36 |
Formula | C20H17NO6 |
CAS No. | 485-49-4 |
Storage
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Solubility Information
DMSO: 36.7 mg/mL (100 mM)
Ethanol: <1 mg/mL
( < 1 mg/ml refers to the product slightly soluble or insoluble )