Caspofungin acetate is an echinocandin antifungal targeting the fungal cell membrane and inhibiting β(1,3)-D-Glucan synthase, a component necessary for cell wall synthesis. Caspofungin acetate is useful against Aspergillus and Candida species.
Caspofungin acetate is often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
MOLECULAR BIOLOGY GRADE
Formula: C52H88N10O15 ∙ 2C2H4O2
MW: 1,213.42 g/mol
Storage/Handling: Store at -20°C.
PubChem Chemical ID: 66577041