Cyclosporin A

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92.00342.00

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Description

The cyclosporins are a group of macrolide immunosuppressants isolated from fungi. They are researched for their use in prevention of post-transplant graft rejection. Their mechanism of action involves suppression of cytotoxic T-cell maturation and activity by binding lymphocyte protein cyclophilin. Cyclophilin and cyclosporin form a complex targeting calcineurin, which is responsible for activating T-lymphocytes. Additionally, the cyclosporins are researched for their ability to prevent damage to normal functioning cells in autoimmune disorders.

Cyclosporin A is over 99% pure and soluble in DMSO and ethyl alcohol.

Product Specifications
Cyclosporin A

Formula: C62H111N11O12

MW: 1,202.61 g/mol

Storage/Handling: Store at 2-8°C.  Soluble in DMSO and EtOH.

PubChem Chemical ID: 5284373

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

Additional information

CatalogID

C-940-100, C-940-500

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