Cyclosporin B

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Description

The cyclosporins are a group of macrolide immunosuppressants isolated from fungi. They are researched for their use in prevention of post-transplant graft rejection. Their mechanism of action involves suppression of cytotoxic T-cell maturation and activity by binding lymphocyte protein cyclophilin. Cyclophilin and cyclosporin form a complex targeting calcineurin, which is responsible for activating T-lymphocytes. Additionally, the cyclosporins are researched for their ability to prevent damage to normal functioning cells in autoimmune disorders.

Cyclosporin B is soluble in DMSO and ethyl alcohol.

Product Specifications
Cyclosporin B

Formula: C61H109N11O12

MW: 1,188.58 g/mol

Storage/Handling: Store at 2-8°C.  Soluble in DMSO and EtOH.

PubChem Chemical ID: 6450331

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

Additional information

CatalogID

C-942-5

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