Cyclosporin C

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258.00926.00

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Description

The cyclosporins are a group of macrolide immunosuppressants isolated from fungi. They are researched for their use in prevention of post-transplant graft rejection. Their mechanism of action involves suppression of cytotoxic T-cell maturation and activity by binding lymphocyte protein cyclophilin. Cyclophilin and cyclosporin form a complex targeting calcineurin, which is responsible for activating T-lymphocytes. Additionally, the cyclosporins are researched for their ability to prevent damage to normal functioning cells in autoimmune disorders.

Cyclosporin C is soluble in DMSO and ethyl alcohol.

Product Specifications
Cyclosporin C

Formula: C62H111N11O13

MW: 1,218.61 g/mol

Storage/Handling: Store at -20°C.
Soluble in DMSO and EtOH

PubChem Chemical ID: 53395167

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

Additional information

CatalogID

C-943-1, C-943-10, C-943-25, C-943-5, C-943-50

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