Doxorubicin HCl, USP Grade





Doxorubicin HCl is an anthracycline antibiotic that inhibits cancer progression by suppressing DNA replication. It is the 12-hydroxylated form of daunorubicin and causes DNA intercalation. It also inhibits topoisomerase II. Doxorubicin is researched for its efficacy against non-Hodgkin’s lymphoma, multiple myeloma, acute leukemias, Kaposi sarcoma, Wilm tumor, Ewing sarcoma, and cancers of the breast, lung, ovary, endometrium, and adrenal cortex. Doxorubicin is an MRP-1 substrate and has been used in drug-resistance studies.

Product Specifications
Doxorubicin HCl, USP Grade

Formula: C27H29NO11 ∙ HCl

MW: 579.98 g/mol

Storage/Handling: Store desiccated at 2-8 °C.  Product is light and moisture sensitive.

PubChem Chemical ID: 443939

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

Additional information


D-490-1, D-490-100, D-490-500


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