Erlotinib HCl

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148.00500.00

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Description

Erlotinib HCl is an anti-cancer agent targeting epidermal growth factor receptor (EGFR) tyrosine kinase ATP binding sites, which are commonly overexpressed and sometimes mutated in a variety of cancers. Erlotinib prevents the formation of EGFR homodimers leading to suppression of signal transmittance and tumor growth inhibition. Additionally, erlotinib suppresses cyclin-dependent kinase 2 (Cdk2). It has been shown to be effective against non-small cell lung cancer and pancreatic cancer.

Product Specifications
Erlotinib HCl
Tarceva®

MOLECULAR BIOLOGY GRADE

Formula: C22H23N3O4

MW: 393.44 g/mol

Storage/Handling: Store at 2-8 °C.  Product is soluble in acid (pH 2) at 0.4 mg/mL.

PubChem Chemical ID: 176870

Air shipments may require special packaging and a small additional box charge.

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

Additional information

CatalogID

E-270-1, E-270-100

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