Methotrexate sodium salt is an anti-cancer agent that works by inhibiting folic acid metabolism. Methotrexate is an allosteric dihydrofolate reductase (DHFR) inhibitor. DHFR is is an essential enzyme in folic acid metabolism. Folic acid is necessary for production of thymidine and purine; therefore, methotrexate is a nucleic acid synthesis inhibitor. It is freely soluble in aqueous solution.
Methotrexate Sodium Salt
MOLECULAR BIOLOGY GRADE
MW: 498.40 g/mol
Storage/Handling: Store desiccated at 2-8°C. Product is sensitive to light. Hygroscopic.
PubChem Chemical ID: 11329481