Mitoxantrone HCl is an anthracenedione anti-cancer agent. It functions by intercalating between DNA and causing double-stranded breaks. This inhibits T-cell, B-cell, and macrophage division and prevents DNA repair and synthesis. It has been shown to be effective against breast cancers, leukemias, and non-Hodgkin’s lymphoma. It also exhibits immunosuppressive activity by inducing apoptosis in antigen-presenting T-cells and is an immune system regulator in multiple sclerosis.
MOLECULAR BIOLOGY GRADE
Formula: C22H28N4O6 ∙ 2HCl
MW: 517.40 g/mol
Storage/Handling: Store at 2-8°C.
PubChem Chemical ID: 51082