Streptozocin is an anti-tumor agent reserved as a last resort against metastatic pancreatic islet cells. Streptozocin functions by adding methyl and alkyl groups to DNA and interfering with normal base pairing. This damages the DNA and causes a decrease in tumor size. Streptozocin enters cells via the glucose transport protein, GLUT2. It is capable of causing vasorelaxation, NCOAT inhibition, and donating nitric oxide (NO).
MOLECULAR BIOLOGY GRADE
MW: 265.22 g/mol
Storage/Handling: Store desiccated at -20°C. Store under inert gas. Hygroscopic.
PubChem Chemical ID: 29327
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